Twisted? Yes. Addicting? Also yes.
The mobile game Plague Inc. takes the whole civilization-building thing in the other direction: the goal is to wipe out all humans on Earth before a cure can be researched. (Admittedly, the synthetic biology industry would probably be humanity’s saving grace in such a scenario, but don’t take it personally.) Users begin the game by selecting a plague type — bacteria, virus, fungus, parasite, prion, nano-virus, and bio-weapon — each of which comes with advantages and disadvantages regarding transmission, symptoms, and special abilities.For more on games go to Can Video Games Inspire the Next Generation of Biohackers? Author: Maxx Chatsko 09 Jun 2014
Source: Plague Inc.
Similar to Spore, your microbe evolves new abilities when enough DNA points are acquired from reaching specific milestones. However, the milestones in Plague Inc. involve infecting new nations, catching a ride on a new form of transportation along major travel routes (sea, air, land), and wiping out large swaths of humans.
Now consider, in a culture of death everything moves toward chaos and annihilation: art, literature, stage and screen, education, laws, music, etc. Fortunately today's technology allows an "underground" resistance movement to flourish as well so we have many who are promoting the true, the good, and the beautiful. Join the resistance and disseminate something good and beautiful today! Here's mine: Vivaldi's Summer from the Four Seasons.